MISSENSE MUTATION IN THE SECOND RNA BINDING DOMAIN REVEALS A ROLE FOR PRKRA (PACT/RAX) DURING SKULL DEVELOPMENT.

Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development.

Random chemical mutagenesis of the mouse genome can causally connect genes to specific phenotypes.Using this approach, reduced pinna (rep) or microtia, Kids clothes a defect in ear development, was mapped to a small region of mouse chromosome 2.Sequencing of this region established co-segregation of the phenotype (rep) with a mutation in the Prkra

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Craft-based design for innovation: Potential in novelty, quality and sustainability through hands-on interaction

The industrial revolution created a rise in mass manufacture, increasing consumption to current unsustainable levels and marking a decline in hands-on craft practice.In contemporary practice, designers frequently employ digital ways of working and, whilst this may create opportunities and efficiencies, it can limit the Originals Classic Sweatshirt

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Experimental study of coupling response characteristics of offshore monopiles, seabed, and waves in various sea conditions

Abstract As the global pursuit of renewable energy intensifies and the demand for offshore wind turbines rises, a comprehensive understanding of the coupling response characteristics of offshore monopiles, seabed, and waves in various sea conditions has become increasingly crucial.This paper reports on a wave flume experiment and seeks to contribut

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Fatal outcome with pregnancy and COVID-19

Introduction: Multiple deaths and infections due to the new coronavirus have occurred.In the midst of this context, the spread of the disease in pregnant patients has been well documented.Objective: Present the events that occurred in pregnant women, in order to share the experience with those who treat these patients.Presentation of the case: The

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